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Hypoxia-driven metabolic shifts reduce intracellular iron availability through increased lactate production, limiting Fenton reaction-mediated lipid peroxidation

Plotted data were mined from the CTRP database, which contains correlation coefficients between gene expression and drug sensitivity for 860 cancer cell lines treated with 481 compounds

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doi: 10.1161/ATVBAHA.109.194589 186

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